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Friday, August 28, 2015

Psoriasis medication

Biologic medication for psoriasis

Psoriasis is a shameful disease, so most people hide lesions. Bonfires lit place themselves in such areas of the body (knees, elbows, scalp, sometimes in the vicinity of cross-lumbar region), so they are easy to hide.

If the disease is mild, it is on the skin appear a single red-brown papules, which are covered with silvery scales, and in severe cases the disease takes large areas of the skin (ie., Plaque psoriasis) or the entire surface (figure erythrodermic).

According to the study, psoriasis is a disease that impairs the quality of life in all areas. It can be compared with coronary heart failure, myocardial infarction or diabetes. People with psoriasis have a great sense of rejection by society, and approx. 15% of patients suffering from mild depression.

Psoriasis is a systemic disease, where inflammation is spread throughout the body and it promotes obesity, the development of diabetes or hypertension. 20-30% of patients have taken joints, and chronic gastrointestinal diseases (e.g.., Crohn's disease, ulcerative colitis), those persons affected five times more likely than the general population. In people with psoriasis increases the risk of cardiovascular disease.

Biologics treat psoriasis

If a patient with psoriasis had failed standard therapy, this aid may come biologics. The effects are impressive.

This will reduce the amount of medication taken by choregos, this leads to remission of the disease and increases the time between exacerbations. Biologics are used in many European countries for over 14 years.

How do the biologic medication?

They act on lymphocytes and cytokines. Psoriasis is now treated with four drugs: etanercept, infliximab, adalimumab and the latest ustekinumab. The fastest running infliximab.

The drug is administered intravenously and yield a dramatic improvement of the skin within a few days. The other three drugs are administered subcutaneously.

The full effect of biological agents therapy will only be evident after several weeks.

Warning! Therapy can not be interrupted, because the symptoms return.


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